Lymphotoxin-𝛼 Plays Only a Minor Role in Host Resistance to Respiratory Infection with Virulent Type A Francisella tularensis in Mice

Table 1

Comparison of cell populations in the bronchoalveolar lavage fluid of LTα−/− and LTα+/+ mice on day 2 and 4 following low-dose aerosol inoculation with type A F. tularensis.

Days post-inoculation	Mouse strain	Total cell count (× 10^5)^(a)	Differential counts (%)
			Macrophages	Lymphocytes	Neutrophils
2	LTα−/−	2.91±1.59	97.60±0.89	2.00±1.00	0.40±0.55
	LTα+/+	1.96±0.31	98.80±0.84	0.40±0.55	0.80±0.84
4	LTα−/−	3.02±0.76	95.20±3.27	2.40±1.52	2.40±1.82
	LTα+/+	2.70±0.55	94.80±6.76	0.20±0.45	5.00±6.82

^(a) The total leukocyte counts are expressed as absolute numbers, and differential counts are expressed as percentages. All data are mean ± standard deviation (n = 5) in each group at each time point. No significant differences were observed between LTα−/− and LTα+/+ mice at any time point.