Homocysteine May Involve in the Pathogenesis of Behcet's Disease by Inducing Inflammation

Table 1

Comparision of serum homocysteine, TNF-α, CRP, and ESR values and BDAI scores between groups.

		Homocysteine (𝜇mol/L)	TNF-α (pg/mL)	ESR (mm/h)	CRP (mg/L)	BDAI scores
		Median (range)
Group I (active BD) (𝑛=34)		20.95 (13.7–39.25)	93.5 (30–228)	24 (2–95)	20.5 (3–400)	16 (9–25)
Group II (inactive BD) (𝑛=36)		13 (6.43–18)	19 (15–30)	27 (8–49)	6.65 (3–34)	2 (1–5)
Group III (healthy control) (𝑛=33)		8 (5–8)	0 (0–18)	6 (2–18)	3.1 (3–10)
Significance for groups	I-II-III	^a𝑃=.00^∗	^a𝑃=.00^∗	^a𝑃=.00^∗	^a𝑃=.00^∗	^c𝑃=.00^∗
	I-II	^b𝑃=.00^∗	^b𝑃=.00^∗	^b𝑃=.001^∗	^b𝑃=.00^∗
	I-III	^b𝑃=.00^∗	^b𝑃=.00^∗	^b𝑃=.00^∗	^b𝑃=.00^∗
	II-III	^b𝑃=.00^∗	^b𝑃=.00^∗	^b𝑃=.008^∗	^b𝑃=.00^∗

^a𝑃^∗ Significantly different by Kruskal-Wallis test (𝑃<.05).^b𝑃^∗ Significantly different by Bonferroni corrected Mann-Withney U test (𝑃<.0167).^c𝑃^∗ Significantly different by Mann-Withney U test (𝑃<.05).Data are presented as median values and their individual ranges within parentheses.