Clinical Study

Homocysteine May Involve in the Pathogenesis of Behcet's Disease by Inducing Inflammation

Table 4

The significance of the association of TNF-α with versus without individual clinical manifestations and pathergy reaction.

TNF-α levels (pg/mL) in patients withTNF-α levels (pg/mL) in patients without
ManifestationsNo. of patientsMedian(Range)Median(Range)P-values

Oral ulcer3170(15–228)20(15–150)
Genital ulcer2354(17–228)21(15–228)
Ocular lesion1899(30–228)21(15–180)
Vascular lesion3784(15–228)21(15–145)
Arthritis/arthralgia2538(15–228)28(15–228)
EN/PPE3145(15–228)22(15–228)
(+) pathergy3545(15–228)21(15–228)

by Mann-Whitney U test (statistically significant with versus without clinical manifestations).Data are presented as median values and their individual ranges within parentheses.