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Mediators of Inflammation
Volume 2008, Article ID 619704, 7 pages
Research Article

Proinflammation and Hypertension: A Population-Based Study

1Unit of Family Practice, Central Hospital of Middle Finland, 40620 Jyväskylä, Finland
2Department of Family Medicine, School of Public Health and Clinical Nutrition, Unit of Family Practice, Kuopio University Hospital, Kuopio University, 70211 Kuopio, Finland
3Department of Rheumatology, Rheumatism Foundation Hospital, 18120 Heinola, Finland

Received 21 April 2008; Revised 3 October 2008; Accepted 8 November 2008

Academic Editor: Charles Larry Campbell

Copyright © 2008 Mauno Vanhala et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. L. X. Fu, “Do immune system changes have a role in hypertension?” Journal of Hypertension, vol. 13, no. 11, pp. 1259–1265, 1995. View at Publisher · View at Google Scholar
  2. Z. Pausova, B. Deslauriers, D. Gaudet et al., “Role of tumor necrosis factor-a gene locus in obesity and obesity-associated hypertension in French Canadians,” Hypertension, vol. 36, no. 1, pp. 14–19, 2000. View at Google Scholar
  3. J.-M. Fernandez-Real, M. Vayreda, C. Richart et al., “Circulating interleukin 6 levels, blood pressure, and insulin sensitivity in apparently healthy men and women,” The Journal of Clinical Endocrinology & Metabolism, vol. 86, no. 3, pp. 1154–1159, 2001. View at Publisher · View at Google Scholar
  4. H. D. Sesso, L. Wang, J. E. Buring, P. M. Ridker, and J. M. Gaziano, “Comparison of interleukin-6 and C-reactive protein for the risk of developing hypertension in women,” Hypertension, vol. 49, no. 2, pp. 304–310, 2007. View at Publisher · View at Google Scholar
  5. A. Syrenicz, B. Garanty-Bogacka, M. Syrenicz, A. Gebala, G. Dawid, and M. Walczak, “Relation of low-grade inflammation and endothelial activation to blood pressure in obese children and adolescents,” Neuroendocrinology Letters, vol. 27, no. 4, pp. 459–464, 2006. View at Google Scholar
  6. L. Sun, Y. H. Gao, D. K. Tian et al., “Inflammation of different tissues in spontaneously hypertensive rats,” Acta Physiologica Sinica, vol. 58, no. 4, pp. 318–323, 2006. View at Google Scholar
  7. Y. Dörffel, C. Lätsch, B. Stuhlmüller et al., “Preactivated peripheral blood monocytes in patients with essential hypertension,” Hypertension, vol. 34, no. 1, pp. 113–117, 1999. View at Google Scholar
  8. V. M. Campese, Y. Shaohua, and H. Zhong, “Downregulation of neuronal nitric oxide synthase and and interleukin-1beta mediates angiotensin II-dependent stimulation of sympathetic nerve activity,” Hypertension, vol. 39, no. 2, part 2, pp. 519–524, 2002. View at Google Scholar
  9. S. Ye, P. Mozayeni, M. Gamburd, H. Zhong, and V. M. Campese, “Interleukin-1β and neurogenic control of blood pressure in normal rats and rats with chronic renal failure,” American Journal of Physiology, vol. 279, no. 6, pp. H2786–H2796, 2000. View at Google Scholar
  10. M. Barbieri, L. Ferrucci, A. M. Corsi et al., “Is chronic inflammation a determinant of blood pressure in the elderly?” American Journal of Hypertension, vol. 16, no. 7, pp. 537–543, 2003. View at Publisher · View at Google Scholar
  11. G. N. Dalekos, M. Elisaf, E. Bairaktari, O. Tsolas, and K. C. Siamopoulos, “Increased serum levels of interleukin-1β in the systemic circulation of patients with essential hypertension: additional risk factor for atherogenesis in hypertensive patients?” Journal of Laboratory and Clinical Medicine, vol. 129, no. 3, pp. 300–308, 1997. View at Google Scholar
  12. N. Molnarfi, L. Gruaz, J.-M. Dayer, and D. Burger, “Opposite regulation of IL-1β and secreted IL-1 receptor antagonist production by phosphatidylinositide-3 kinases in human monocytes activated by lipopolysaccharides or contact with T cells,” The Journal of Immunology, vol. 178, no. 1, pp. 446–454, 2007. View at Google Scholar
  13. U. Salmenniemi, E. Ruotsalainen, J. Pihlajamäki et al., “Multiple abnormalities in glucose and energy metabolism and coordinated changes in levels of adiponectin, cytokines, and adhesion molecules in subjects with metabolic syndrome,” Circulation, vol. 110, no. 25, pp. 3842–3848, 2004. View at Publisher · View at Google Scholar
  14. A. C. T. M. Peeters, M. G. Netea, M. C. H. Janssen, B. J. Kullberg, J. W. M. van der Meer, and T. Thien, “Pro-inflammatory cytokines in patients with essential hypertension,” European Journal of Clinical Investigation, vol. 31, no. 1, pp. 31–36, 2001. View at Publisher · View at Google Scholar
  15. B. Vohnout, A. Di Castelnuovo, R. Trotta et al., “Interleukin-1 gene cluster polymorphisms and risk of coronary artery disease,” Haematologica, vol. 88, no. 1, pp. 54–60, 2003. View at Google Scholar
  16. H. Cha-Molstad, A. Agrawal, D. Zhang, D. Samols, and I. Kushner, “The Rel family member P50 mediates cytokine-induced C-reactive protein expression by a novel mechanism,” The Journal of Immunology, vol. 165, no. 8, pp. 4592–4597, 2000. View at Google Scholar
  17. L. Niskanen, D. E. Laaksonen, K. Nyyssönen et al., “Inflammation, abdominal obesity, and smoking as predictors of hypertension,” Hypertension, vol. 44, no. 6, pp. 859–865, 2004. View at Publisher · View at Google Scholar
  18. W. Vongpatanasin, G. D. Thomas, R. Schwartz et al., “C-reactive protein causes downregulation of vascular angiotensin subtype 2 receptors and systolic hypertension in mice,” Circulation, vol. 115, no. 8, pp. 1020–1028, 2007. View at Publisher · View at Google Scholar
  19. S. J. Zieman, V. Melenovsky, and D. A. Kass, “Mechanisms, pathophysiology, and therapy of arterial stiffness,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 25, no. 5, pp. 932–943, 2005. View at Publisher · View at Google Scholar
  20. P. M. Ridker, J. E. Buring, J. Shih, M. Matias, and C. H. Hennekens, “Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women,” Circulation, vol. 98, no. 8, pp. 731–733, 1998. View at Google Scholar
  21. W. Wang, E. T. Lee, R. R. Fabsitz et al., “A longitudinal study of hypertension risk factors and their relation to cardiovascular disease: the strong heart study,” Hypertension, vol. 47, no. 3, pp. 403–409, 2006. View at Publisher · View at Google Scholar
  22. J. He, M. J. Klag, L. J. Appel, J. Charleston, and P. K. Whelton, “Seven-year incidence of hypertension in a cohort of middle-aged African Americans and whites,” Hypertension, vol. 31, no. 5, pp. 1130–1135, 1998. View at Google Scholar
  23. G. Mancia, G. De Backer, A. Dominiczak et al., “2007 Guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC),” Journal of Hypertension, vol. 25, no. 6, pp. 1105–1187, 2007. View at Publisher · View at Google Scholar
  24. M. Ufnal, M. Dudek, T. Zera, and E. Szczepańska-Sadowska, “Centrally administered interleukin-1 beta sensitizes to the central pressor action of angiotensin II,” Brain Research, vol. 1100, no. 1, pp. 64–72, 2006. View at Publisher · View at Google Scholar
  25. C.-J. Zou, J.-D. Liu, and Y.-C. Zhou, “Roles of central interleukin-1 on stress-induced-hypertension and footshock-induced-analgesia in rats,” Neuroscience Letters, vol. 311, no. 1, pp. 41–44, 2001. View at Google Scholar
  26. P. A. Sarafidis, A. I. Kanaki, and A. N. Lasaridis, “Statins and blood pressure: is there an effect or not?” Journal of Clinical Hypertension, vol. 9, no. 6, pp. 460–467, 2007. View at Publisher · View at Google Scholar
  27. J.-J. Li, Y.-S. Li, J.-M. Chu et al., “Changes of plasma inflammatory markers after withdrawal of statin therapy in patients with hyperlipidemia,” Clinica Chimica Acta, vol. 366, no. 1-2, pp. 269–273, 2006. View at Publisher · View at Google Scholar
  28. M. A. Fisher, G. W. Taylor, B. J. Shelton, and S. Debanne, “Age and race/ethnicity-gender predictors of denying smoking, United States,” Journal of Health Care for the Poor and Underserved, vol. 19, no. 1, pp. 75–89, 2008. View at Publisher · View at Google Scholar