Effects of Radix Adenophorae and Cyclosporine A on an OVA-Induced Murine Model of Asthma by Suppressing to T Cells Activity, Eosinophilia, and Bronchial Hyperresponsiveness

Table 2

Effects of RAE on CD4+/CD8−, GR-1+/CD11b+, IgE+/B220+, and CD3e+/CD69+ cells absolute number in lymph nodes and BAL fluid of OVA-induced asthma murine.

Cell phenotype	Organ	Normal C57BL/6	OVA-induced asthma mice (Absolute no.)
			Control	CsA	RAE (450)	RAE (45)
CD4^+/CD8^− (×10^4 cells)	LN^1	221.9 ± 34.9	232.7 ± 12.8	150.3 ± 41.1∗∗	193.95 ± 10.1∗	244.7 ± 32.2
	BA^2	3.9 ± 0.6	33.6 ± 0.8	13.2 ± 3.1∗∗	11.3 ± 0.1∗∗	27.7 ± 1.5∗
Gr-1^+/CD11b^+ (×10^4 cells)	LN^1	25.6 ± 0.5	73.6 ± 13.8	45.0 ± 11.9∗∗	33.7 ± 1.0∗∗	45.6 ± 8.6∗
IgE^+/B220^+ (×10^4 cells)	LN^1	3.6 ± 0.1	6.6 ± 1.2	3.6 ± 1.1	2.1 ± 0.3∗	3.0 ± 0.9
	BA^2	0.3 ± 0.01	2.6 ± 0.07	0.5 ± 0.03∗∗	0.5 ± 0.02∗∗	1.1 ± 0.05∗
CD3^+/CD69^+ (×10^4 cells)	LN^1	32.5 ± 3.0	54.2 ± 1.4	35.6 ± 8.1	36.6 ± 1.9	47.6 ± 7.1