Effects of Radix Adenophorae and Cyclosporine A on an OVA-Induced Murine Model of Asthma by Suppressing to T Cells Activity, Eosinophilia, and Bronchial Hyperresponsiveness

Table 3

Effect of RAE on Eotaxin2, CCR3, IL-13, IL-10, TNF-𝛼, and TARC mRNA expression in lung tissue of OVA-induced murine model of asthma (NM: normal C57BL/6 mice; CT: OVA-induced asthma mice (control); CsA: OVA-induced asthma mice treated with cyclosporine A (10 mg/kg); RAE 45 mg/kg: OVA-induced asthma mice treated with RAE (450 mg/kg); RAE 450 mg/kg: OVA-induced asthma mice treated with RAE (450 mg/kg)).

OVA/alum	Group	Exotaxin2	CCR3	IL-10	IL-13	TARC	TNF-𝛼
−	NM	0.02	0.03	0.05	0.016	0.656	0.152
+	CT	1	1	1	1	1	1
+	CsA	0.202	0.404	0.621	0.386	0.12	0.255
+	RAE (450 mg/kg)	0.462	0.499	0.577	0.284	0.487	0.401
+	RAE (45 mg/kg)	0.62	0.725	0.504	0.763	0.944	0.625