Serum Concentration of Interleukin-6 Is Increased Both in Active and Remission Stages of Pemphigus Vulgaris

Table 1

Interleukin-1 (IL-1), interleukin-6 (IL-6), and tumor necrosis factor-𝛼 (TNF-𝛼) concentrations in serum samples from patients with active stage of pemphigus vulgaris (PV active), remission stage of PV (PV remission), and in normal controls.

Cytokines	PV active 𝑁=19	PV remission 𝑁=24	Controls 𝑁=19
IL-1 (pg/mL)
Median	0.3	0.5	0.3
(Interquartile range, 25th–75th)	0.1–0.7	0.3–0.7	0.1–0.4
IL-6 (pg/mL)
Median	3.38	2.58	1.97
(Interquartile range, 25th–75th)	2.72–4.98	2.085–3.86	1.64–2.25
TNF-𝛼 (pg/mL)
Median	6.2	53.05	3.9
(Interquartile range, 25th–75th)	4.1–100	2.8–100	3.4–5.6