Research Article

Interleukin (IL)-4 Induces Leukocyte Infiltration In Vivo by an Indirect Mechanism

Figure 3

IL-4 increases CCL2 protein expression in the exudates. Air pouches was created as described in Materials and Methods and 1 ml of the buffer (Ctrl), LPS (1  g/ml), or IL-4 (250 ng/ml) were administered into the pouch. Exudates were harvested after 6, 9, 12 and 24 hours, pooled ( ) and then CCL2 production was measured by ELISA.
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