Figure 2: Inflammatory response (TNF-α secretion) of CD patient’s PBMCs in presence of somatostatin analogs. CD patients PBMCs (5·  cells/mL) were activated by LPS for 24 hours in presence of increasing doses of somatostatin analogs (  M to  M). Quantitative evaluation of the secreted cytokine TNF-α was done by sandwich ELISA as described in Materials and Methods.