Effects of Methotrexate on Plasma Cytokines and Cardiac Remodeling and Function in Postmyocarditis Rats
Figure 2
Macroscopic and microscopic assessment of the hearts. (a) Representative gross appearance of the heart from each group of rats. (b) Representative photomicrographs of the ventricular sections (HE staining; 200). In hearts from the control group, myocytes is well organized. In EAM60 group, the cardiac myocytes exhibited extensive necrosis, degeneration, and disorder. MTX treatment led to a significant decrease in the size of these lesions.
