Research Article
Effects of Methotrexate on Plasma Cytokines and Cardiac Remodeling and Function in Postmyocarditis Rats
Table 2
Comparison of echocardiograph parameters of all three groups rats on day 60 (n = 10).
| Groups | Control | EAM60 | EAM-MTX |
| LVEDD (mm) | 5.69 ± 0.29 | | △ | LVESD (mm) | 2.24 ± 0.30 | | 0.41*,▲ | LVPWT (mm) | 1.74 ± 0.17 | | 1.65 ± 0.21 | IVST (mm) | 1.76 ± 0.17 | | 1.68 ± 0.20 | LVMI (mg/g) | 1.52 ± 0.04 | 1.62 ± 0.17 | 1.60 ± 0.14 | RWT | 1.73 ± 0.24 | | 1.86 ± 0.35 | FS (%) | 62.31 ± 6.86 | | 55.02 ± 4.16*,▲ | LVEF (%) | 89.87 ± 4.40 | | 84.77 ± 3.60▲ | SV (L) | 162.38 ± 25.39 | | 156.02 ± 15.29△ |
|
|
, versus control group; △P < .05, ▲P < .01 versus EAM60 group.
|