Effects of Ubiquinol-10 on MicroRNA-146a Expression In Vitro and In Vivo

Table 1

Concentration and redox state of CoQ₁₀ in the human monocytic cell line THP-1 after incubation with various concentrations of ubiquinol-10 for 24 hours. Data are given as means ± SD of two independent measurements performed in duplicate.

Extracellular		Cellular
μM ubiquinol-10	pmol CoQ10/10^6 cells	% ubiquinol-10	μM ubiquinol-10^((a)-(b))
0, medium control	25.62±4.42	74.40±0.14	4.56
0, vehicle control	23.07±0.46	74.70±1.56	4.12
0.1	24.68±2.01	75.25±0.35	4.44
1.0	26.48±3.36	79.35±0.07	5.03
10.0	72.35±1.14	86.10±0.71	14.90
100	627.46±138.08	90.35±1.48	140.35

^(a)Suggested diameter of monocytes: 20 μm
^(b)Related to mean values.