Research Article

Persistently Elevated Level of IL-8 in Chlamydia trachomatis Infected HeLa 229 Cells is Dependent on Intracellular Available Iron

Figure 5

IL-8 induction was significantly increased in C. trachomatis infected HeLa cells after stimulation with DETA-NANOate and there was synergic effect with DFO. Glucose oxidase treatment induced IL-8 production at same degree in both the C. trachomatis infected and Mock conditions . Higher inhibition of IL-8 induction was observed after addition of nitric oxide specific inhibitor PDTC than ebselen.
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