Activation of TLR4-Mediated NFB Signaling in Hemorrhagic Brain in Rats
Figure 2
The temporal changes of TLR4 protein in brain tissue after ICH. The expression of TLR4 protein was measured in brain tissue by the method of Western Blots using specific antibody for TLR4. The signals were quantified by scanning densitometry and computer-assisted image analysis and expressed as the ratio of TLR4 protein to GAPDH. The results showed that low level of TLR4 protein was detectable in the saline control group. The expression of TLR4 significantly increased starting from 6 hours after ICH (), peaked on 3 days after ICH, and then decreased but still maintained at a high level on 7 days after ICH (). #: compared with saline control, ; *: compared with 6 hours after ICH, .
