Local C-Reactive Protein Expression in Obliterative Lesions and the Bronchial Wall in Posttransplant Obliterative Bronchiolitis

Table 2

Correlations (R) to the grade of bronchial wall CRP. R is given for assessment points with statistical significance (𝑃<.05). The grade of CRP expression in the bronchial wall turned out to correlate to the inflammatory alterations and bronchial remodeling processes. Correlations are given from the follow-up day 14 onward. On the follow-up day 14 onward, grade of CRP expression was significantly (𝑃<.0001) more intense in allografts than in autografts.

Mural inflammation	CRP/day 14	CRP/day 17	CRP/day 21	CRP/day 28
day 14	0.658
day 17	0.823	0.900
day 21	0.834	0.522	0.720
day 28	0.879	0.590	0.693	0.716
N of CD4+ cells	CRP/day 14	CRP/day 17	CRP/day 21	CRP/day 28
day 14	0.764
day 17	0.663	0.815
day 21	0.480	0.532	0.669
day 28	0.456	0.516	0.595	0.551
N of CD8+ cells	CRP/day 14	CRP/day 17	CRP/day 21	CRP/day 28
day 14	0.487
day 17	0.741	0.874
day 21	0.568	0.600	0.672
day 28	0.528	0.475	0.689	0.591
Mural fibrosis	CRP/day 14	CRP/day 17	CRP/day 21	CRP/day 28
day 14	0.739
day 17		0.864
day 21	0.525	0.737	0.804
day 28	0.642	0.926	0.841	0.747
Luminal obliteration	CRP/day 14	CRP/day 17	CRP/day 21	CRP/day 28
day 14	0.845
day 17	0.795	0.797
day 21	0.813	0.810	0.875
day 28	0.811	0.848	0.868	0.870