Serologic Investigations in Children with Inflammatory Bowel Disease and Food Allergy

Table 2

Comparison between the frequency of occurrence of ANCA and ASCA antibodies in groups.

	Controls	UC	CD	Allergy colitis	𝑃
pANCA (+) (%)	—	25	10.5	17.6	.04∗
cANCA (+) (%)	—	10	—	—	.04∗∗
IgA ASCA (+) (%)	4.3	7.5	57.9	17.6	<.00001∗∗∗
IgG ASCA (+) (%)	4.3	17.5	71.1	29.4	<.00001∗∗∗∗
ASCA IgG and/or IgA (%)	8.7	17.5	73.7	29.4	<.00001∗∗∗∗∗
Combinations ANCA and ASCA (%)					<.00001∗∗∗∗∗∗
pANCA(+)ASCA(+)	0	2.5	5.3	0
pANCA(+)ASCA(−)	0	22.5	5.3	17.7
pANCA(−)ASCA(+)	8.7	15	68.4	29.4
pANCA(−)ASCA(−)	91.3	60	21.1	52.9

∗UC versus Ctrl, 𝑃=.01.
∗∗In exact Fisher’s test there are not any significant relations while comparing groups in pairs.
∗∗∗CD versus Ctrl, 𝑃<.00001; CD versus UC, 𝑃<.00001; CD versus AC, 𝑃=.008.
∗∗∗∗CD versus Ctrl, 𝑃<.00001; CD versus UC, 𝑃<.00001; CD versus AC, 𝑃=.007.
∗∗∗∗∗CD versus Ctrl, 𝑃<.00001; CD versus UC, 𝑃<.00001; CD versus AC, 𝑃=.003.
∗∗∗∗∗∗Concerning combination pANCA(−)ASCA(+): CD versus Ctrl, 𝑃<.00001; CD versus UC, 𝑃<.00001; CD versus AC, 𝑃=.009.