Inhibitory Effects of Ketamine on Lipopolysaccharide-Induced Microglial Activation
Figure 3
Effect of ketamine
on interleukin (IL)-1β production in lipopolysaccharide (LPS)-activated microglia. Microglia
( cells m) were treated with ketamine (100 and 250 μM) or an isovolumetric PBS buffer
for 30 minutes, followed by the addition of LPS
(100 ng m) for 12
hours. Cell-free supernatants were assayed for IL-1β production as described in Section 2. Data are
presented as the means ± S.E.M. (). , compared to the
resting group; and , compared to
the PBS-treated group.
