Mediators of Inflammation / 2009 / Article / Fig 1

Research Article

Influence of Epinastine Hydrochloride, an H 1 -Receptor Antagonist, on the Function of Mite Allergen-Pulsed Murine Bone Marrow-Derived Dendritic Cells In Vitro and In Vivo

Figure 1

Influence of epinastine hydrochloride (EP) on immunomodulatory cytokine production from dendritic cells (DCs) stimulated with Dermatophagoides farinae (Der f) in vitro. DCs derived from bone marrow of BALB/c mice were stimulated with Der f in the presence of various concentrations of EP for 24 hours. IL-10 and IL12p40 levels in culture supernatants were examined by ELISA. The data are expressed as the mean pg/mL ± SE of triplicate cultures. This is one of two different experiments, which gave reproducible results.

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