Leptin Induces an Inflammatory Phenotype in Lean Wistar Rats
Figure 4
Effect of leptin on hepatocytes. Human C3A hepatocytes were cultured in the presence of leptin (0–125 ng/mL) for 24 hours. (a) The release of soluble ICAM-1 into the culture medium and (b) ICAM-1 mRNA levels was quantified by ELISA and real-time PCR, respectively. Statistics were performed using one-way ANOVA P< .05 compared to vehicle control cultures.
