Th1 and Th2 Immune Response in Chronic Hepatitis B Patients during a Long-Term Treatment with Adefovir Dipivoxil

Table 1

Demographic profiles of study participants.

Parameters	Chronic HBV patients	Health volunteers
No.	22	20
Age (years)
Mean ± SD	45.9±8.1	38.5±11.8^∗
Median	46	36.5
Range	30–61	25–58
Sex N(%)
Male	17 (77.3)	14 (70)
Female	05 (22.7)	6 (30)
Years from HBV diagnosis
Mean ± SD	10.3±1.6	NA
HBV DNA (log10 copies/ml)
Mean	5.8	NA
SD	0.2
ALT (U/L)
Median	27.6	15.4*
Range	10.1–445.6	5.6–37.5
AST (U/L)
Median	26.8	11.3*
Range	7.1–312.4	2.5–25.4
HbsAg (log10 IU/ml)
Median	1082.5	NA
Range	90.0–12795.0

* Differences between treatment groups and health volunteers were statistically significant (𝑃<.5).