Th1 and Th2 Immune Response in Chronic Hepatitis B Patients during a Long-Term Treatment with Adefovir Dipivoxil

Table 2

Comparison of intracellular Th1/Th2 cytokines in chronic HBV patients and healthy volunteers.

Parameters (% CD3+CD4+)	Patients (no. 22)	Healthy volunteers (no. 20)	𝑃 value
IL-4	0.4 (0–6.0)	5.69 (1.99–14.22)	<.0001
IFN-γ	0.4 (0–9.4)	5.73 (3.78–12.09)	<.0001
IL-2	0.6 (0–7.0)	12.16 (4.44–17.82)	<.0001
IL-10	0.6 (0–3.8)	11.70 (6.87–21.32)	<.0001
TNF-α	0.7 (0.1–14.3)	15.75 (7.25–27.41)	<.0001

The data were expressed as median % and range.
^∗∗𝑃 value for all treatment were statistically different between patients and healthy volunteers (<.0001).