Th1 and Th2 Immune Response in Chronic Hepatitis B Patients during a Long-Term Treatment with Adefovir Dipivoxil

Table 5

Comparison of serum cytokine in chronic HBV patients and healthy volunteers.

Cytokine (pg/mL)	Patients (no. 22)	Healthy volunteers (no. 20)	𝑃value
IL-4	4.5 (2.2–6.5)	3.0 (1.4–14.9)	0.016**
IFN-γ	5.85 (1.6–8.8)	4.4 (1.8–84.5)	0.009**
IL-2	5.5 (3.5–7.3)	2.3 (0.6–10.1)	0.044**
IL-10	5.7 (3.4–10.5)	1.6 (1.0–28.4)	0.499
TNF-α	2.9 (1.5–3.5)	1.6 (0.6–21.8)	0.032**

*The data were expressed as median % and range.
^∗∗𝑃 value for all treatment were statistically different between patients and healthy volunteers (<.05).