Clinical Study

Circulating Cytokine Profiles and Their Relationships with Autoantibodies, Acute Phase Reactants, and Disease Activity in Patients with Rheumatoid Arthritis

Table 3

Serum cytokine, chemokine, and growth factor values for the total RA cohort 𝑛 = 1 4 0 .

Mean ± SD*Q1(p25)*Q2 (Median)*Q3 (p75)*Range*

IL-1β 2 4 . 8 ± 4 8 1.45.320.00–269
IL-Ra 3 6 3 . 5 ± 7 9 3 25.374.8266.10–5012
IL-2 4 4 . 7 ± 1 5 5 0.00.030.20–1320
IL-4 3 0 . 5 ± 8 4 0.13.613.30–598
IL-6 6 4 . 7 ± 1 3 0 6.818.365.50–1078
IL-7 2 2 1 . 1 ± 7 4 1 4.922.289.50–6825
IL-8 2 9 5 . 5 ± 3 1 1 1 5.09.320.20–36699
IL-10 4 1 . 6 ± 1 3 4 3.910.725.80–1172
IL-12 1 2 3 . 9 ± 4 0 4 2.211.054.31–3105
IL-17A 6 . 0 ± 2 6 0.00.00.260–229
G-CSF 2 2 6 . 9 ± 8 4 2 0.014.357.90–8764
GM-CSF 1 1 2 . 8 ± 3 7 5 0.00.031.00–3726
IFN-γ 5 8 0 . 1 ± 1 5 8 8 0.031.3195.50–10922
CCL2 8 9 . 0 ± 2 0 0 0.050.7107.40–1771
CCL4 1 3 2 . 6 ± 9 4 70.4108.2171.727–544
TNF 1 4 9 . 6 ± 4 3 4 4.311.661.91–2952
VEGF 4 5 0 . 4 ± 7 1 2 59.4166.4518.80–4503

*results in pg/mL.