Examining the Genomic Influence of Skin Antioxidants In Vitro

Table 4

Summary of fibroblasts genes noted to be commonly downregulated by the antioxidant treatments.

FIBROBLASTS	Test Materials	Pomiferin	Osajin	Resveratrol	EGCG	Genistein	Rosavin	Puerarin	Chlorogenic Acid	Propolis
Gene Name	Gene Description
DSG3	Desmoglein 3	0.847	0.545	0.708	0.667	−0.118	0.385	0.438	0.46	0.737
HAS1	Hyaluronan synthase 1	1.091	0.667	0.526	0.615	0.695	0.429	0.462	1.5	0.385
ILIA	Interleukin 1, alpha	1.2	0.599	0.588	0.556	−0.27	0	0.5	0.517	0.5
KL	Klotho	1.136	0.731	0.56	0.7	0.099	0.167	0.588	0	0.7
NOS2	Nitric oxide synthase 2	0.831	0.694	0.655	0.928	0.303	0.441	0.588	1.05	0.724
PGR	Progestone receptor	0.764	0.926	0.579	0.571	0.337	0.364	0.583	0	0.545