Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli

Table 2

The skin surface lipid (SSL) composition (%) and total lipid content in adult healthy subjects and in adult patients suffering from seborrheic dermatitis (HIV-negative and HIV-positive) and atopic dermatitis (according to [29, 30]).

Lipid Fraction	Groups
	Healty subjects ($n=30$)	Seborrheic dermatitis ($n=30$)	Seborrheic dermatitis (HIV positive) ($n=30$)	Atopic dermatitis ($n=20$)
Squalene (SQ)	12.8 $\pm$ 0.6	11.7 $\pm$ 0.9*	11.5 $\pm$ 1.0*	10.8 $\pm$ 1.1*
Cholesterol esters (CE)	1.3 $\pm$ 0.2	1.0 $\pm$ 0.4	1.8 $\pm$ 0.5*	2.4 $\pm$ 0.6*
Wax esters (WE)	25.6 $\pm$ 3.2	23.9 $\pm$ 5.1	23.8 $\pm$ 4.5	21.7 $\pm$ 1.8*
Triglycerides (TG)	36.1 $\pm$ 8.4	40.7 $\pm$ 10.3	42.3 $\pm$ 10.2	32.6 $\pm$ 10.6
Free fatty acids (FFA)	21.6 $\pm$ 8.8	18.9 $\pm$ 9.6	17.4 $\pm$ 10.5	28.8 $\pm$ 11.4
Cholesterol (CH)	1.2 $\pm$ 0.2	1.7 $\pm$ 0.5*	1.7 $\pm$ 0.5*	2.4 $\pm$ 0.4*
Diglycerides (DG)	1.4 $\pm$ 0.2	1.2 $\pm$ 0.2	1.5 $\pm$ 0.2	1.3 $\pm$ 0.2
TOTAL LIPIDS ($\mu$g/cm^2)	195.4 $\pm$ 20.6	171.2 $\pm$ 29.7*	167.2 $\pm$ 30.4*	172.6 $\pm$ 17.4*

SSL sampled from the forehead, with diethyl ether cup extraction method [30]. Results are expressed as mean $\pm$ S.D.
*Significance level versus healthy subjects at $P<.05$.