Possible Implication of Local Immune Response in Darier's Disease: An Immunohistochemical Characterization of Lesional Inflammatory Infiltrate
Figure 2
The inflammatory infiltrate in Darier’s disease is mostly constituted by CD4+ T lymphocytes (a), with less numerous CD8+ T (b), and a few CD20+ B (c) lymphocytes. Redstained, FOXP3+ nuclei of Tregs are shown in (d) Immunohistochemistry; original magnification, 200; Scale bar = 75 m; Chromogen: fuchsin.