Possible Implication of Local Immune Response in Darier's Disease: An Immunohistochemical Characterization of Lesional Inflammatory Infiltrate

Figure 3

Few CD1a+ LCs (an intraepidermal CD1a+ LC is indicated by the arrow), small in size, and without evident dendrites, in two cases of Darier’s disease ((a), (b)). Normal skin showing more numerous, larger CD1a+ LCs, with long dendrites (c). An increased number of both epidermal and dermal CD1a+ LCs in a case of lichen ruber planus (d). Immunohistochemistry. Original magnification, $\times$200; Scale bar = 75 $\mu$m; Chromogen: fuchsin ((a), (b)); diaminobenzidine ((c), (d)).

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(b)

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(d)