Changes in Glucose and Glutamine Lymphocyte Metabolisms Induced by Type I Interferon α

Table 1

Proliferation of splenocytes and mesenteric lymphocytes cultured in the presence or absence of IFNα.

	No add	ConA	LPS
C LFN	1003.6 ± 65.3	1954.5 ± 87.5	1753.1 ± 103.2
IFN LFN	875.4 ± 65.8^†	1478.3 ± 76.3^†	1165.9 ± 55.9^†
C SPL	1231.2 ± 81.9	2309.6 ± 117.4	1987.3 ± 80.2
IFN SPL	845.1 ± 76.4^♦	1543.9 ± 67.1^♦	1456.3 ± 87.3^♦

The values are expressed as disintegrations per minute (DPM) and are presented as mean ± SEM of 9 experiments. ConA: concanavalin A; LPS: lipopolysaccharide; C LFN: mesenteric lymphocytes incubated in the absence of IFNα; IFN LFN; mesenteric lymphocytes cultured with IFNα; C SPL: splenocytes cultured in the absence of IFNα; SPL IFN splenocytes cultured with IFNα. ^† 𝑃<.05 compared to C LY group. ^♦𝑃<.05 compared with C SPL group.