Effects of Brain-Derived Neurotrophic Factor on Local Inflammation in Experimental Stroke of Rat

<table>BDNF modulating local cytokine in brain after stroke Interleukin10 (IL10) and tumor necrosis factor <i>α</i> (TNF-<i>α</i>) in rat brain after stroke were measured using ELISA kits. (a) Exogenous BDNF upregulated IL-10 24 h after reperfusion while BDNF antibody decreased IL-10 6 h after reperfusion. (b) Exogenous BDNF decreased TNF-<i>α</i> at 6 h and 24 h of reperfusion than control group and BDNF antibody overwhelmed the effect. Bars represent mean ± SD (<svg height="9.8999996" id="M139" style="vertical-align:-0.1575pt" version="1.1" viewbox="0 0 31.475 9.8999996" width="31.475" xmlns="http://www.w3.org/2000/svg">
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<tspan style="font-size: 11.21px; " x="23.357471" y="0">0</tspan>
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Mediators of Inflammation

fig5

Figure 5

Figure 5: Effects of Brain-Derived Neurotrophic Factor on Local Inflammation in Experimental Stroke of Rat 