The Potency of Hyaluronan of Different Molecular Weights in the Stimulation of Blood Phagocytes
Figure 2
Effect of different MW HA (100 μg/mL) on spontaneous (a, b), PMA-activated (c, d), OZP-activated (e, f), and starch-activated (g, h) ROS production measured in diluted whole blood by luminol-enhanced chemiluminescence in absence (a, c, e, g) and presence of collagen (0.16 mg/mL) (b, d, f, h), immediately or after 1.5 h pre-incubation after addition of HA. The bold line represents the median, and data points from parallel measurements are presented by the same symbol. Statistically significant differences among different groups () are marked by different symbols: (*) statistical significance to control, (#) statistical significance to sample incubated with 52 kDa HA, and ($) statistical significance between samples incubated with 250 kDa and 970 kDa HA.
