Mediators of Inflammation / 2010 / Article / Fig 1

Research Article

Effect of Feeding Status on Adjuvant Arthritis Severity, Cachexia, and Insulin Sensitivity in Male Lewis Rats

Figure 1

Body mass (a) and food intake (b) in control rats on standard diet (CN =▲), high-fat diet (SHF = ■), and food restriction (FR =♦), and in arthritic rats on standard diet (AA-N = ∆), high-fat diet (AA-SHF = □), and food restriction (AA-FR=) in selected days after cFA inoculation. Values for food intake are presented as means of 2 cages (4 rats per cage). Statistical significance between the body mass values in arthritic rats and their corresponding controls on the same dietary regime: *P<.05, **P<.01, ***P<.001. Significant difference between AA-N and AA-SHF: P<.05. First day of significant differences: CN versus SHF ×P<.05, FR versus CN aP<.05, FR versus SHF bP<.001, AA-FR versus AA-N ###P<.001, and AA-FR versus AA-SHF +++P<.001. Effects of dietary interventions on the severity of arthritis expressed by arthrogram score (c). Significant difference between AA-FR and AA-N: *P<.05, ***P<.001; significant difference between AA-FR and AA-SHF: +++P<.001; significant difference between AA-SHF and AA-N: P<.05.

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