The Decreased Growth Hormone Response to Growth Hormone Releasing Hormone in Obesity Is Associated to Cardiometabolic Risk Factors

Table 1

Clinical characteristics, cardiovascular risk markers, and hepatic aminotransferases in obese premenopausal women ($n=48$).

	Mean$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$SEM
Age (year)	32.6$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$2.6
BMI (kg/${\text{m}}^2$)	36.0$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$1.6
Mid-waist circumference (cm)	102.4$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$3.4
Waist/hip ratio	0.90$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$0.02
Total body fat ($\%$)	38.7$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm$ 1.5
Trunk fat (c${\text{m}}^2$)	141.9$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$10.2
GH Peak (ng/mL)	10.4$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$1.8
IGF-I (ng/mL)	147.3$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$69.0
Total cholesterol (mg/dL)	177.1$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$11.2
HDL (mg/dL)	52.6$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$2.0
LDL (mg/dL)	106.3$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$9.6
Triglyceride (mg/dL)	102.4$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$18.3
Fasting glucose (mg/dL)	95.7$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm$ 2.0
Fasting Insulin ($\mu$U/mL)	13.0$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$0.5
HOMA-IR	3.3$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$0.5
TAS	122.5$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$3.5
TAD	76.5$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$3.2
Leptin (ng/mL)	24.3$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$13.5
GOT (IU/L)	21.4$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$8.0
GPT (mIU/L)	24.9$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$12.7
GGT (IU/L)	25.6$\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}$27.3