Research Article

Release of Danger Signals during Ischemic Storage of the Liver: A Potential Marker of Organ Damage?

Figure 2

Liver damage during ischemic storage. Liver enzymes in the effluent increased gradually in parallel to the length of warm/cold ischemia time. Mean total liver enzymes values were higher, but not significantly ( 𝑃 > . 0 5 ) ((a) and (b)). Liver injury was confirmed by liver histology (original magnification, 200x). Progressive changes in hepatocyte morphology such as cell dissociation (D), cytoplasmic vacuolization (V), and nuclear pycnosis (P) did increase over ischemia time. (c) 0 h cold ischemia (CI) liver tissue; (d) 24 h CI liver tissue.
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(a)
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(b)
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(c)
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(d)