Relevance of Serum Leptin and Leptin-Receptor Concentrations in Critically Ill Patients

Figure 3

Prognostic relevance of serum leptin-receptor in critically ill patients. (a) Kaplan-Meier survival curves of ICU patients ($n=137$) are displayed, showing that patients with high leptin-receptor levels ($>$32 ng/m/L, black) have an increased mortality as compared to patients with low serum leptin-receptor ($\le$32 ng/mL, grey). $P$-value from Cox regression analysis is  .034. (b) Patients that die during follow-up period treatment ($n=71$, 51.8%) have significantly ($P=.037$) higher serum leptin-receptor levels on admittance to ICU than survivors ($n=66$, 48.2%). Box plot are displayed, where the dotted line indicates the median per group, the box represents 50% of the values, and horizontal lines show minimum and maximum values of the calculated nonoutlier values; asterixes and open circles indicate outlier values.

(a)

(b)