Mediators of Inflammation / 2010 / Article / Tab 1

Clinical Study

Relevance of Serum Leptin and Leptin-Receptor Concentrations in Critically Ill Patients

Table 1

Characteristics of the study population.

ParameterAll ICU patientsSepsisNonsepsis

Number1379542
Sex (number male/number female)85/5259/3626/16
Sex (% male/female)62/3862/3862/38
Age median (years) (range)63 (18–81)64 (20–81)60 (18–79)
BMI median (kg/m²) (range)25.4 (15.3–59.5)25.65 (15.3–59.5)24.9 (17.5–37.4)
Days at ICU median (range)8 (1–137)10 (1–137)6 (1–45)
Days in hospital median (range)25 (2–151)30 (2–151)14 (2–85)
Death at ICU n (%)41 (29.9)30 (31.6)11 (26.2)
Death during follow-up n (%)71 (51.8)49 (51.6)22 (52.4)
C-reactive protein median (mg/dL) (range)112 (5–230)167 (5–230)14.5 (5–164)
Procalcitonin median (μg/L) (range)0.9 (0.1–207.5)2.2 (0.1–207.5)0.2 (0.1–36.5)
IL-6 median (ng/L) (range)110 (2–1000)170 (7.7–1000)40.5 (2–1000)
IL-10 median (ng/L) (range)16 (5–1500)20 (5–1500)5.9 (5–750)
Protein median (g/L) (range)52.5 (21–77)52 (21–77)55.5 (31–73)
Prothrombin time median (%) (range)73 (11–100)75 (11–100)69 (13–100)
Creatinine median (mg/dL) (range)1.6 (0.1–13.1)1.9 (0.1–10.7)1.2 (0.3–13.1)
Cystatin C median (mg/L) (range)1.76 (0.41–7.30)1.89 (0.41–6.33)1.34 (0.41–7.30)
Glucose median (mg/dL) (range)134 (47–663)126 (47–299)155 (65–663)
Insulin median (mU/L) (range)9.8 (0.2–1000)7.7 (0.2–438.0)25.0 (0.2–1000)
C-peptide median (nmol/L) (range)1.66 (0–13.0)1.56 (0–13.0)2.01 (0–11.6)
APACHE II score median (range)14 (0–31)14 (0–31)15 (0–28)
SAPS-2 score median (range)43 (0–80)43 (0–79)41.5 (13–80)

BMI: body mass index; IL: interleukin; ICU: intensive care unit; APACHE: Acute Physiology and Chronic Health Evaluation.

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