Systemic Inflammation in Chronic Obstructive Pulmonary Disease: May Adipose Tissue Play a Role? Review of the Literature and Future Perspectives

<table>Concept of differential contribution of lung-to-blood translocation of inflammatory proteins versus adipose tissue inflammation to the overall systemic inflammatory phenotype in COPD. We suggest that in patients with mild COPD and concurrent obesity, adipose tissue (AT) is the key contributor to systemic inflammation, whereas in those with severe COPD, lung-to-blood translocation of inflammatory proteins plays the major role.</table>

Mediators of Inflammation

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Figure 1: Systemic Inflammation in Chronic Obstructive Pulmonary Disease: May Adipose Tissue Play a Role? Review of the Literature and Future Perspectives 

Figure 1 | Systemic Inflammation in Chronic Obstructive Pulmonary Disease: May Adipose Tissue Play a Role? Review of the Literature and Future Perspectives 