Systemic Inflammation in Chronic Obstructive Pulmonary Disease: May Adipose Tissue Play a Role? Review of the Literature and Future Perspectives

<table>Proposed mechanistic links between the combined effects of obesity-related local adipose tissue hypoxia, reduced lung function-related systemic hypoxia, and bronchial inflammation-related increased lung-to-plasma translocation of inflammatory mediators on systemic inflammatory profile in patients with COPD.</table>

Mediators of Inflammation

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Figure 2: Systemic Inflammation in Chronic Obstructive Pulmonary Disease: May Adipose Tissue Play a Role? Review of the Literature and Future Perspectives 

Figure 2 | Systemic Inflammation in Chronic Obstructive Pulmonary Disease: May Adipose Tissue Play a Role? Review of the Literature and Future Perspectives 