Research Article

Leptin Administration Downregulates the Increased Expression Levels of Genes Related to Oxidative Stress and Inflammation in the Skeletal Muscle of ob/ob Mice

Table 3

Bivariate analysis of the correlations between TBARS concentrations in serum and the gastrocnemius muscle with anthropometric and biochemical variables in wild type and ob/ob mice.

SerumTBARSGastrocnemiusTBARS
ρPρP

Body weight0.57.0090.46.040
Glucose0.44.0550.38.103
FFA0.54.0150.59.007
Glycerol0.49<.0010.44.053
TG0.44.0540.44.050
Insulin0.49.0270.52.020
Adiponectin-0.51.022-0.53.016
QUICKI-0.48.031-0.48.033
HOMA0.53.0190.51.025

Values are Spearman's correlation coefficients (ρ) and associated P values. TBARS: thiobarbituric acid reactive substances. FFA: free fatty acids. TG: triglycerides. HOMA: homeostasis model assessment. QUICKI: quantitative insulin sensitivity check index.