Expression of CYLD and NF-𝜅B in Human Cholesteatoma Epithelium

Figure 1

Immunohistochemistry of CYLD in cholesteatoma epithelium and normal retroauricular (RA) skin. (a): CYLD in normal RA skin. (b): CYLD in cholesteatoma epithelium. Note that strong CYLD immunoreactivity was observed mainly in the cytoplasm of cells in the basal and suprabasal epithelial layers of normal RA skin, whereas weak expression was detected in the cytoplasm of cells in the basal layer of the cholesteatoma epithelium. Bar$=$300 $\mu$m. (c): Rates of positive labeling for CYLD in cholesteatoma epithelium and normal RA skin. The rate of cells positive for CYLD was significantly lower in cholesteatoma epithelium than in normal RA skin. Data are presented as means$\pm$SD. ${}_{}{}^{*}P<.05$.

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