Expression of CYLD and NF-𝜅B in Human Cholesteatoma Epithelium

Figure 2

Immunohistochemistry of NF-κB in cholesteatoma epithelium and normal retroauricular (RA) skin. (a): NF-κB in normal RA skin. (b): NF-κB in cholesteatoma epithelium. Note that strong expression was observed in the nuclei of cells in the basal and suprabasal layers of cholesteatoma epithelium, whereas weak NF-κB immunoreactivity was mainly seen in the cytoplasm of cells in the basal epithelial layers of normal RA skin. Bar$=$300 $\mu$m. (c) Rates of positive labeling for NF-κB in the nuclei of cells in cholesteatoma epithelium and normal RA skin. The rate of cells positive for NF-κB was significantly higher in cholesteatoma epithelium than in normal RA skin. Data are presented as means$\pm$SD. ${}_{}{}^{*}P<.05$.

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