Regulation of I𝜅B𝛼 Function and NF-𝜅B Signaling: AEBP1 Is a Novel Proinflammatory Mediator in Macrophages

Table 1

I𝜅B𝛼-Interacting Proteins and Impact on NF-𝜅B Activity.

I𝜅B𝛼-Interacting Protein	Species	I𝜅B𝛼-Interacting Region	Interaction Region of I𝜅B𝛼	Impact on NF-𝜅B Activity	Reference
X protein	Hepatitis B Virus	Unknown	C-terminus (aa 249-253)	↑	[314]
𝛽-arrestin2	Homo sapiens	N-terminus (aa 1-60)	C-terminus (aa 276-317)	↓	[315]
FBI-1	Homo sapiens	POZ domain (aa 24-131)	Unknown	↑	[316]
AEBP1	Mus musculus	DLD (aa 1-166)	Unknown	↑	[266]
ChlaDub1	Chlamydia trachomatis	Unknown	Unknown	↓	[317]
GRK5	Homo sapiens	RH domain (aa 50–176)	N-terminus (aa 1–58)	↓	[318]
N^pro	Classical Swine Fever Virus	Unknown	C-terminus (aa 213–317)	↔	[319]