Distribution of Major Basic Protein on Human Airway following In Vitro Eosinophil Incubation
Figure 9
Distribution of immunoreactive MBP and nerve PGP 9.5 in human airway following overnight incubation with human eosinophils. Representative images of 2 mm human airway incubated overnight with eosinophils. Immunoreactive PGP 9.5 (green) and MBP (red) are shown. Though some eosinophils appeared near nerves (small arrows) in the human airway (a), many eosinophils, as well as extracellular MBP deposition, occurred within the airway wall not associated with airway nerves (b) (thick arrows) under higher magnification (confocal microscopy 400x).
