Table 1: Renal histopathological features of the mice in different groups (n=68). The degree of severity of histological lesions was evaluated as absent (-), mild (+), moderate (++), and severe (+++).

GroupGlomerulonephritisRenal tubular lesionsInterstitial inflammation
AtrophyCapillary walls thickeningMesangial broadeningDilationEpithelial cells proliferationProtein castsInflammatory cells infiltrationFibroblasts proliferation

Normal--------
Model++++++/+++++++/+++++++/+++++
Pre++++/+++/++-~+++-
MT1+++++++++++++++
MT2++++++-~+++-
MT3+-/++-/+-/+-/++-