Redox Responses in Patients with Sepsis: High Correlation of Thioredoxin-1 and Macrophage Migration Inhibitory Factor Plasma Levels

Table 3

Comparison of IL-6, TRX1, and MIF plasma levels in the volunteer, postoperative, and septic group at baseline.

	Healthy ($n=18$)	Post-OP ($n=28$)	Sepsis ($n=15$)
IL-6 (pg/ml)	0.0; 0.0–0.8	216.7; 48.8–360.5	577.7; 521.9–583.2
$P$-value	Healthy versus Post-OP: $P<.001$***
	Healthy versus Sepsis: $P<.001$***
	Post-OP versus Sepsis: P <.001***
TRX1 (ng/ml)	11.0; 10.0–12.1	11.3; 9.6–15.6	34.0; 19.7–57.7
$P$-value	Healthy versus Post-OP: $P=.458$
	Healthy versus Sepsis: $P<.001$***
	Post-OP versus Sepsis: P <.001***
MIF (pg/ml)	161.6; 148.5–214.0	156.4; 115.1–398.7	1821.1; 412.2–3708
$P$-value	Healthy versus Post-OP: $P=.954$
	Healthy versus Sepsis: $P=.005$**
	Post-OP versus Sepsis: $P<.001$***

Data are presented by median and interquartile range (Q1–Q3).