Leptin, Adiponectin, and Obesity among Caucasian and Asian Women

Table 2

Association of leptin and adiponectin with CRP by ethnicity^a.

	All women^b (𝑛=182)		Asian (𝑛=74)		Caucasian (𝑛=67)
	β (95% CI)	P ^c	β (95% CI)	P ^c	β (95% CI)	P ^c	P ^d
Overall
Leptin	0.40 (0.05, 0.76)	0.03	0.36 (−0.32, 1.04)	0.30	0.32 (−0.27, 0.91)	0.29	0.52
Adiponectin	−0.25 (−0.63, 0.12)	0.18	−0.18 (−0.83, 0.48)	0.59	−0.27 (−0.93, 0.39)	0.43	0.68
Normal weight (BMI < 25 kg/m^2)
Leptin	0.49 (0.09, 0.90)	0.02	0.31 (−0.44, 1.06)	0.41	0.53 (−0.13, 1.19)	0.12	0.67
Adiponectin	0.08 (−0.49, 0.65)	0.78	0.39 (−0.54, 1.32)	0.41	−0.06 (−1.09, 0.96)	0.91	0.52
Overweight/obese (BMI ≥ 25 kg/m^2)
Leptin	0.66 (0.19, 1.13)	0.01	1.34 (0.56, 2.12)	<0.01	0.64 (−0.12, 1.39)	0.10	0.21
Adiponectin	−0.58 (−1.07, −0.09)	0.02	−0.95 (−1.74, −0.16)	0.02	−0.75 (−1.60, 0.09)	0.08	0.74

Abbreviations: BMI: body mass index, CRP: C-reactive protein.
^aValues are estimates from analysis of covariance of CRP, 95% confidence intervals (CI), and P values. CRP, leptin, and adiponectin were log-transformed for all models. Model adjusted for BMI (continuous) and ethnicity (Asian, Caucasian, Native Hawaiian/other ethnic groups) as appropriate.
^bOne woman with missing CRP measurement was excluded from analyses.
^c𝑃- value for the association between leptin or adiponectin and CRP.
^d𝑃- value for interaction by ethnicity.