Antiasthmatic Effects of Hesperidin, a Potential Th2 Cytokine Antagonist, in a Mouse Model of Allergic Asthma
Figure 1
(a) Schematic diagram of methacholine-induced AHR in the sensitization protocol. (b) PenH was measured with a Buxco box, as described in Materials and Methods. *, ** for control goup versus HPN-treated groups (c), effect of HPN on histology of lung tissue (H&E, M-T, and PAS staining) in lung cells of the OVA-induced murine model of asthma. H&E: hematoxylin-eosin stain, M-T: Masson trichrome stain, PAS: Periodic acid-Schiff stain, N: normal BALB/c mice, CT (control): Ovalbumin inhalation + vehicle, OVA + formoterol (1 mg/kg), OVA + HPN (5, 1 mg/kg).
