Nuclear Factor-Kappa B Activity Regulates Brain Expression of P-Glycoprotein in the Kainic Acid-Induced Seizure Rats

Table 1

NF-𝜅B p65 expression in each group (the number of cases).

groups	CA3 area				DG				AMYG
	I	II	III	IV	I	II	III	IV	I	II	III	IV
NS group	7	1	0	0	8	0	0	0	5	3	0	0
EP group	1	4	2	5	2	4	4	2	1	3	2	6
PDTC group	8	4	0	0	7	5	0	0	3	6	3	0
DEX group	6	3	0	3	4	8	0	0	2	3	6	1
𝑃^∗	𝑃=.001				𝑃=.000				𝑃=.002
EP versus NS	𝑃=.001				𝑃=.003				𝑃=.001
PDTC versus EP	𝑃=.001				𝑃=.006				𝑃=.015
DEX versus EP	𝑃=.057				𝑃=.025				𝑃=.141

Note: Values are presented as 4 distinct grades: I: ≤25% (rare); II: 26%–50% (sparse); III: 51%–75% (high); IV: >75% (all), according to the proportions of NF-𝜅B positive cells. *The overall difference among 4 groups using the Kruskal-Wallis test. DG: dentate gyrus; AMYG: amygdaloid nuclear.