Nuclear Factor-Kappa B Activity Regulates Brain Expression of P-Glycoprotein in the Kainic Acid-Induced Seizure Rats

Table 2

P-gp expression in the rat brain of each group (the number of cases).

groups	CA3 area				DG				AMYG
	I	II	III	IV	I	II	III	IV	I	II	III	IV
NS group	7	1	0	0	8	0	0	0	8	0	0	0
EP group	0	2	9	1	2	4	6	0	2	3	6	1
PDTC group	7	5	0	0	10	2	0	0	7	5	0	0
DEX group	0	10	2	0	5	6	0	1	2	3	6	1
𝑃^∗	𝑃=.000				𝑃=.000				𝑃=.001
EP versus NS	𝑃=.000				𝑃=.001				𝑃=.001
PDTC versus EP	𝑃=.000				𝑃=.001				𝑃=.004
DEX versus EP	𝑃=.001				𝑃=.058				𝑃=.029

Note: Values are presented as 4 distinct grades: I: ≤25% (rare); II: 26%–50% (sparse); III: 51%–75% (high); IV: >75% (all), according to the proportions of P-gp positive cells. *The overall difference among 4 groups using the Kruskal-Wallis test. DG: dentate gyrus; AMYG: amygdaloid nuclear.