Apelin Serum Level in Egyptian Patients with Chronic Hepatitis C
Table 1
Demographic, clinical characteristics, and studied parameters of all participants.
Groups/parameters
Control
Liver disease
12
73
Age (years)
51 ± 3.7
52.4 ± 5.8
NS
Gender (M/F)
6/6
48/25
NS
BMI (Kg/m2)
23 ± 1.6
28.7 ± 5.2
BMI (18.5–24.9), lean (%)
12 (100%)
37 (51%)
BMI (30–35), obese (%)
0
36 (49%)
ASC/fibrosis/cirrhosis
—
20/20/33
Fatty liver
—
14 (19%)
Portal hypertension* and/or ascites
—
20 (27%)
HOMA-IR§
1.85 (1.63–2)
3.28 (2.3–4.7)
0.001
IR (%)
—
43 (59%)
TNF-α (pg/mL)§
76.6 (43–141)
297.0 (205.5– 457.2)
<0.0001
Apelin (ng/mL)§
1.11 (0.83–1.42)
3.25 (2.6–3.9)
<0.0001
Data are mean ± S.D, -male to female ratio, § = median (25th and 75th centiles-quartiles). *surrogate markers of portal hypertension, esophageal varices, splenomegaly, and thrombocytopenia.
