Gene Expression Profiling in Lungs of Chronic Asthmatic Mice Treated with Galectin-3: Downregulation of Inflammatory and Regulatory Genes
Figure 4
Immunohistochemical expression of SOCS-3 in lung tissue from A/J mice. (a) Saline control group (untreated). (b) Positive control group (OVA group) with chronic allergic airway inflammation. (c) pEGFP group, OVA immunized animals treated with empty plasmid. (d) pEGFP-Gal-3 group, OVA immunized animals treated with plasmid encoding Gal-3. (e) Control using normal goat IgG instead of goat anti-SOCS3 antibody. The picture is a representative example of 5 mice, all displaying similar results.